Atlas
Coagulation

Activated partial thromboplastin timeaPTT

Intrinsic and common pathway; monitors UFH and screens for factor deficiencies.

Sample
Citrated plasma
Clinical reference range
25 to 35 s
Adult
Conv: 2535 s
Biology

What it measures

Surface-activated cascade through factors XII → XI → IX → VIII → common pathway.

Clinical use

Why we order it

Heparin monitoring, hemophilia, lupus anticoagulant.

Differential

Causes of abnormal values

Causes of HIGH
  • UFH
  • Hemophilia A/B (factor VIII/IX)
  • vWD
  • Lupus anticoagulant
  • Liver disease (late)
Related

Related biomarkers