Minerals & trace elements
Phosphate
Essential anion in ATP, DNA, and bone; regulated by PTH and FGF23.
Sample
Serum, fasting
Clinical reference range
2.5 to 4.5 mg/dL
Adult
Conv: 2.5–4.5 mg/dL
Biology
What it measures
85% in bone. Reciprocal regulation with calcium via PTH and FGF23.
Differential
Causes of abnormal values
Causes of HIGH
- ↑CKD
- ↑Hypoparathyroidism
- ↑Tumor lysis
- ↑Rhabdomyolysis
Causes of LOW
- ↓Refeeding syndrome
- ↓DKA recovery
- ↓Vitamin D deficiency
- ↓Antacids (binding)
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